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COMPREHENSIVE METABOLIC PANEL (CMP)

Standard chemistry panel that evaluates kidney function, liver function, blood glucose, electrolyte and fluid balance, and protein levels, used as a broad screen for metabolic disorders, diabetes, and kidney or liver disease.

LIS PANEL CODE: (MID) Comprehensive Metabolic Panel (CMP)

INDIVIDUAL LIS TEST CODES INCLUDED WITHIN PANEL: AGRATIO, ALB, GLOB, TP, TBIL, ALKP, ALT, AST, BUN, CREA, BCR, GFR, CA, GLU, CO2, K, NA, CL, AGP

CPT CODE: 80053

ALIASES: CMP, Chem 14, Chem Panel, Metabolic Panel

METHODOLOGIES: Spectrophotometry, Ion-Selective Electrode (ISE)

SPECIMEN:

- Type: Serum

- Container: Gold Top (SST) Vacutainer

- Minimum Volume Required: 1 mL

- Storage/Handling: Allow 30 minutes for blood to clot, then centrifuge specimen at 3500 RPM for 10 minutes. Maintain specimen at room temperature or in the refrigerator until testing can be performed.

- Stability:   

 

Room Temperature (20-25 °C): 2 hours

Refrigerated (2-8 °C): 3 days 

Frozen (-20 °C or colder): Not Accepted

- Turnaround Time: 24 hours from receipt.

Special Instructions: N/A

REJECTION REASONS: QNS, Gross Hemolysis, Gross Lipemia, Contamination, Stability Violation, Expired Container, Incorrect Container

REFERENCE RANGES: 

A/G Ratio (AGRATIO):

Males & Females

>= 1 year of age: 1.2 - 2.2

Calculated using the following formula: ALB / GLOB

Albumin (ALB):

Males & Females (g/dL)

1 - 30 years of age: 3.7 - 5.1 

31 - 50 years of age: 3.9 - 5.1 

51 - 60 years of age: 3.8 - 4.9 

61 - 70 years of age: 3.9 - 4.9 

71 - 80 years of age: 3.8 - 4.8

81 - 90 years of age: 3.7 - 4.7

> 90 years of age: 3.6 - 4.6​​

Globulin (GLOB): 

Males & Females (g/dL)

 

>= 1 year of age: 1.5 - 4.5

Calculated using the following formula: TP - ALB

Total Protein (TP):

Males & Females (g/dL)

​>= 1 year of age: 6.3 - 7.9

​Total Bilirubin (TBIL):

Males & Females (mg/dL)

1 - 17 years of age: 0.0 - 1.0

>= 18 years of age: 0.0 - 1.2

Panic Threshold(s): >= 15.0 mg/dL for Males & Females >= 18 years of age.

Alkaline Phosphatase (ALKP):

Males (U/L) 

1 - 9 years of age: 142 - 335 

10 - 12 years of age: 129 - 417 

13 - 14 years of age: 116 - 468

15 - 16 years of age: 82 - 331 

17 - 18 years of age: 55 - 149

>= 19 years of age: 40 - 129 

 

Females (U/L) 

1 - 9 years of age: 142 - 335 

10 - 12 years of age: 129 - 417 

13 - 14 years of age: 57 - 254 

15 - 16 years of age: 50 - 117

>= 17 years of age: 35 - 104

Alanine Aminotransferase (ALT):

Males (U/L)

>= 1 year of age: 7 - 55

​​

Females (U/L)

>= 1 year of age: 7 - 45

Aspartate Aminotransferase (AST):

Males (U/L)

1 - 13 years of age: 8 - 60

>= 14 years of age: 8 - 48

Females (U/L)

1 - 13 years of age: 8 - 50

>= 14 years of age: 8 - 43

Panic Threshold(s): >= 10,000 U/L for Males & Females >= 1 year of age.​

Blood Urea Nitrogen (BUN):

Males (mg/dL)

1 - 17 years of age: 7 - 20

>= 18 years of age: 8 - 24

Females (mg/dL)

1 - 17 years of age: 7 - 20

>= 18 years of age: 6 - 21

Creatinine (CREA):

Males (mg/dL)

1 - 5 years of age: 0.19 - 0.49

6 - 10 years of age: 0.26 - 0.61

11 - 14 years of age: 0.35 - 0.86

>= 15 years of age: 0.74 - 1.35

Females (mg/dL)

1 - 5 years of age: 0.19 - 0.49

6 - 10 years of age: 0.26 - 0.61

11 - 15 years of age: 0.35 - 0.86

>= 16 years of age: 0.59 - 1.04

Panic Threshold(s): >= 2.5 mg/dL for Males & Females 1 - 10 years of age; >= 3.0 for Males & Females 11 - 14 years of age; >= 10.0 mg/dL for Males & Females >= 15 years of age.

BUN / Creatinine Ratio (BCR):

Males & Females

>= 1 year of age: 10 - 20

Ratio              Interpretation                 Clinical Context

< 10            Low                                  May suggest liver disease, malnutirition, or low protein intake
10 - 20       Normal                            Typical kidney function
21 - 24       Mildly Elevated               Often indicates dehydration
25 - 29      Moderately Elevated      Reduced kidney perfusion or dehydration
>= 30        Significantly Elevated     May suggest GI bleeding or serious prerenal cause 

Calculated using the following formula: BUN / CREA

Glomerular Filtration Rate (GFR):

Males & Females (mL/min/1.73m^2)

​>= 1 year of age: >= 90 

eGFR Category      eGFR Value             Status of Kidney Function

      G1                     >= 90                      Normal or High
      G2                     60 - 89                  Mildly Decreased
      G3a                   45 - 59                  Mildly to Moderately Decreased
      G3b                   30 - 44                  Moderately to Severely Decreased
      G4                     15 - 29                   Severely Decreased
      G5                      < 15                       Kidney Failure

Calculated using the 2021 CKD-EPI equation, currently recommended by the ASN and NKF for GFR reporting in the United States. This version does not take into account race.

Calcium (CA): 

Males & Females (mg/dL)

2 - 11 years of age: 9.1 - 10.5

12 - 17 years of age: 8.9 - 10.4

18 - 59 years of age: 8.7 - 10.2

>= 60 years of age: 8.6 - 10.3

Panic Threshold(s): <= 6.5 mg/dL; >= 13.0 mg/dL for Males and Females >= 1 year of age.

Glucose, Random (GLU):

Males & Females (mg/dL)

>= 1 year of age: 70 - 140

Panic Threshold(s): <= 50; >= 400 mg/dL for Males & Females >= 1 year of age.

Carbon Dioxide (CO2):

Males (mmol/L)

1 - 3 years of age: 17 - 26

4 - 5 years of age: 19 - 27

6 - 7 years of age: 20 - 28

8 - 17 years of age: 21 - 29

>= 18 years of age: 22 - 29

Females (mmol/L)

1 - 3 years of age: 18 - 25

4 - 5 years of age: 19 - 26

6 - 7 years of age: 20 - 27

8 - 9 years of age: 21 - 28

>= 10 years of age: 22 - 29

​​

Panic Threshold(s): <= 10 mmol/L; >= 40 mmol/L for Males & Females >= 1 year of age.

Potassium (K):

Males & Females (mmol/L)

>= 1 year of age: 3.6 - 5.2

Panic Threshold(s): <= 2.5 mmol/L; >= 6.5 mmol/L for Males & Females >= 1 year of age.

Sodium (NA):

Males & Females (mmol/L)

>= 1 year of age: 136 - 145

Panic Threshold(s): <= 120 mmol/L; >= 160 mmol/L for Males & Females >= 1 year of age.

Chloride (CL):

Males & Females (mmol/L)

1 - 17 years of age: 102 - 112

>= 18 years of age: 98 - 107

Anion Gap (AGP):

Males & Females (mmol/L)

 

>= 1 year of age: 7 - 15

Calculated using the following formula: NA - (CL + CO2)

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44400 Van Dyke Avenue, Sterling Heights, MI 48314

Phone: (586)-991-6985

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