TEST DIRECTORY | MIDx Labs

SEX HORMONE BINDING GLOBULIN (SHBG)

Binding protein used to interpret free testosterone/estrogen status.

LIS TEST CODE: SHBG

CPT CODE: 84270

ALIASES: SHBG, Sex Steroid Binding Protein (SBP)

METHODOLOGY: Chemiluminescent Microparticle Immunoassay (CMIA)

SPECIMEN:

- Type: Serum

- Container: Gold Top (SST) Vacutainer

- Minimum Volume Required: 1 mL

- Storage/Handling: Allow 30 minutes for blood to clot, then centrifuge specimen at 3500 RPM for 10 minutes. Maintain specimen in the refrigerator until testing can be performed.

- Stability: Room Temperature (20-25 °C): Not Accepted

Refrigerated (2-8 °C): 8 days

Frozen (-20 °C or colder): Not Accepted

- Turnaround Time: 24 hours from receipt.

Special Instructions: N/A

REJECTION REASONS: QNS, Gross Hemolysis, Gross Lipemia, Contamination, Stability Violation, Expired Container, Incorrect Container

REFERENCE RANGES:

Males (nmol/L)

1 - 17 years of age: See Comment

Male Children:
Tanner Stages Mean Age Reference Interval (nmol/L)
Stage I 10.4 17.0 - 135.0
Stage II 11.1 21.0 - 114.0
Stage III 12.7 12.0 - 138.0
Stage IV 14.5 7.7 - 67.0
Stage V 14.2 3.9 - 40.0

>= 18 years of age: 13.3 - 89.5

Females (nmol/L)

1 - 17 years of age: See Comment

Female Children:
Tanner Stages Mean Age Reference Interval (nmol/L)
Stage I 10.5 16.0 - 182.0
Stage II 10.9 24.0 - 121.0
Stage III 12.5 18.0 - 87.0
Stage IV 14.0 7.7 - 108.0
Stage V 14.9 10.0 - 79.0

18 - 46 years of age: 18.2 - 135.5

>= 47 years of age: See Comment

Post-menopausal: 16.8 - 125.2 nmol/L

Reference values for pregnant women have not been established.