MICHIGAN INNOVATIVE DIAGNOSTICS

Tumor marker primarily used to monitor ovarian cancer.

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LIS TEST CODE: CA125

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CPT CODE: 86304

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ALIASES: CA125, Carbohydrate Antigen 125, OV Monitor, Ovarian Cancer-Related Antibodies

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METHODOLOGY: Chemiluminescent Microparticle Immunoassay (CMIA)

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SPECIMEN:

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- Type: Serum

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- Container: Gold Top (SST) Vacutainer

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- Minimum Volume Required: 1 mL

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- Storage/Handling: Allow 30 minutes for blood to clot, then centrifuge specimen at 3500 RPM for 10 minutes. Maintain specimen in the refrigerator until testing can be performed.

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- Stability:     

 

Room Temperature (20-25 °C): Not Accepted

Refrigerated (2-8 °C): 7 days

​Frozen (-20 °C or colder): Not Accepted

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- Turnaround Time: 24 - 48 hours from receipt.

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Special Instructions: If testing will be delayed for more than 24 hours, remove serum from the separator gel and transfer into a separate plastic screw-cap transport container.

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REJECTION REASONS: QNS, Gross Hemolysis, Gross Lipemia, Contamination, Stability Violation, Expired Container, Incorrect Container

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REFERENCE RANGES:

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Males (U/mL)

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CA-125 is not recommended as a screening test in male patients. Clinical utility is generally limited to select oncology or serosal disease indications.

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Females (U/mL)

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>= 1 year of age: < 46.0​​

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Serum markers are not specific for malignancy, and values may vary by method.

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